Poliglecaprone suture is a fast absorbing suture made of a synthetic absorbable monofilament composed of glycolide and epsilon-caprolactone copolymer (usually called PGCL suture). It comes both dyed (violet) and un-dyed (clear), and is a monofilament suture. Ethicon are the original inventors of PGCL suture which are available under the brand name Monocryl suture.
Poliglecaprone suture has a low tissue reactivity, maintains high tensile strength, but PGCL suture loses about 40% of its Tensile Strength within 7 to 14 days and loses about 50 to 60% tensile strength by 3 to 4 weeks, and the suture is completely hydrolyzed by 3 to 4 months. Progressive loss of tensile strength and eventual absorption of PGCL suture occurs by means of hydrolysis. Poliglecaprone 25 copolymer has been found to be non-antigenic, non-pyrogenic and elicits only a slight tissue reaction during absorption. Poliglecaprone suture are contraindicated for use in cardiovascular and neurologic tissues, and for usage in ophthalmic and microsurgery. Poliglecaprone suture are rarely used for percutaneous skin closure, and are not used in areas of high tension. . The use of Poliglecaprone suture may be inappropriate in elderly, malnourished, or debilitated patients, or in patients suffering from conditions that may delay wound healing.